Does Prefect 2.0 support key-value store?

Yes! You can leverage blocks to securely store stateful information in your Prefect 2.0 environment:

All block values are encrypted before being stored, and if you want to store Secrets, you can leverage the Secret block:
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There are various types of blocks depending on the type of (configuration) data you would like to store:

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Prefect 1.0 (legacy)

In Prefect 1.0, the equivalent functionality was provided as a key-value store offered only in Prefect Cloud: